NeurosciencebioRxivPreprint
Neuronal targeted AAV Micro-Dystrophin restores neurobehavioural co-morbidities, grip strength and motor coordination in mdx52 mouse model of Duchenne Muscular Dystrophy
Konstantina Tetorou, Mónica Rebeca Gil-Garzon, Darren Chambers…·Francesco Muntoni A
This study evaluates neuronal-targeted AAV micro-dystrophin therapy in mdx52 mice, showing IV delivery improves neurobehavioural, motor, and neuromuscular deficits more effectively than ICV delivery.
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