Mustafa Görkem Özyurt

This study evaluates neuronal-targeted AAV micro-dystrophin therapy in mdx52 mice, showing IV delivery improves neurobehavioural, motor, and neuromuscular deficits more effectively than ICV delivery.

The paper identifies spinal circuits that map trunk regions to control skin twitches in mice, showing somatotopic organization and optogenetic activation of specific motor pathways.

The paper shows that high-frequency common inputs affect motoneuron subpopulations differently, revealing frequency-dependent synchronization masked in whole-pool analyses.

The paper characterizes the cellular and circuit properties of perineal motor control in adult mice, revealing distinct biophysical features and motor unit recruitment patterns during urination.

This study identifies dI3 neurons in the spinal cord that compare efference copies and sensory feedback to enable rapid movement corrections.

This study uses high-density surface EMG and in silico modelling to reveal subject-specific inhibitory spinal microcircuit properties and control strategies.

The paper investigates how spinal microcircuits adapt in a mouse model of motoneuron degeneration, finding specific multiphasic homeostatic compensations that preserve force output.

This study investigates the origin of F-waves in mice, showing they are mediated by spinal microcircuits via glutamatergic synapses from motor axon collaterals.

The paper investigates the spatial organization of spinal premotor interneurons controlling flexor and extensor muscles, finding they are intermingled rather than segregated.

This paper describes two in vitro longitudinal lumbar spinal cord preparations from juvenile mice to study sensory and motor microcircuits using whole-cell patch-clamp electrophysiology.

This study shows that spinal cord dysfunction contributes to DYT1 dystonia by creating mouse models with dystonia-like symptoms.