Author

Mohammed Hoque

Regeneron (United States)ORCID 0000-0002-0221-5094Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

Kei SaotomeiD· 2 shared Tong ZhangiD· 2 shared Anbo ZhouiD· 1 shared Andrew D Baik· 1 shared Andrew J Murphy· 1 shared Danny CheniD· 1 shared Eric SmithiD· 1 shared Feng‐Qian LiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Kei SaotomeORCID

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3 papers

Recent·Most cited

Bacterial major vault protein homologs form divergent vault structures

Jake C Lachowicz, Mohammed Hoque, Anbo Zhou, Tong Zhang, Matthew C Franklin, Richard Copin, Katherine D Cygnar, Andrew J Murphy, Kei Saotome, Andrew D Baik

The paper identifies bacterial MVP homologs and reports cryoEM structures of vaults from Corallococcus praedator and a Deltaproteobacteria bacterium, revealing novel symmetries.

bioRxiv · Nov 9, 2026 · PreprintBiochemistry

Structural characterization of two full length γδTCR/CD3 complexes

Mohammed Hoque, John Benji Grigg, Trudy F. Ramlall, Jennifer L. Jones, Luke L. McGoldrick, John C. Lin, William C. Olson, Eric Smith, Matthew C. Franklin, Tong Zhang, Kei Saotome

This study reports cryoEM structures of two full-length γδ TCR/CD3 complexes, revealing similarities to β TCRs but with highly mobile extracellular domains and a dimeric assembly in one complex.

Nature Communications · Jan 2, 2025Peer-reviewedBiochemistry

The Distal Appendage Protein CEP164 Is Essential for Efferent Duct Multiciliogenesis and Male Fertility

Mohammed Hoque, Danny Chen, Rex A. Hess, Feng‐Qian Li, Ken‐Ichi Takemaru

This study shows that CEP164 is essential for multiciliogenesis in efferent ducts, leading to male infertility due to sperm agglutination and duct obstruction.

Reproduction · Jun 4, 2021Peer-reviewedGenetics