Author

Grazia Graziani

University of Rome Tor VergataORCID 0000-0002-0221-768XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alessandra PaciniiD· 1 shared Alessandra TotiiD· 1 shared Alessia VonaiD· 1 shared Angela Dello StrittoiD· 1 shared Annamaria BiroccioiD· 1 shared Antonella SguraiD· 1 shared Antonio Antoccia· 1 shared C. D’Angelo· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alessandra PaciniORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

TRF1 poly(ADP-ribosyl)ation by PARP1 allows proper telomere replication through helicase recruitment in non-ALT cells

C. Maresca, Angela Dello Stritto, C. D’Angelo, Eleonora Petti, Eleonora Vertecchi, Luca Pompili, Francesco Berardinelli, Antonella Sgura, Antonio Antoccia, Grazia Graziani, Annamaria Biroccio, Erica Salvati

This study shows PARP1 PARylates TRF1 to recruit helicases during telomere replication, preventing DNA damage in non-ALT cells.

bioRxiv · Oct 27, 2021 · PreprintMolecular Biology

VEGF-A/VEGFR-1: a painful astrocyte-mediated signaling blocked by the anti-VEGFR-1 mAb D16F7

Laura Micheli, Carmen Parisio, Elena Lucarini, Alessia Vona, Alessandra Toti, Alessandra Pacini, Tommaso Mello, Serena Boccella, Flavia Ricciardi, Sabatino Maione, Grazia Graziani, Pedro Miguel Lacal, Paola Failli, Carla Ghelardini, Lorenzo Di Cesare Mannelli

This study identifies VEGF-A released by astrocytes as a key mediator of chemotherapy-induced neuropathic pain and shows that the anti-VEGFR-1 mAb D16F7 alleviates this pain.

bioRxiv · Jan 19, 2021 · PreprintNeuroscience