NeurosciencebioRxivPreprint
VEGF-A/VEGFR-1: a painful astrocyte-mediated signaling blocked by the anti-VEGFR-1 mAb D16F7
Laura Micheli, Carmen Parisio, Elena Lucarini…·Lorenzo Di Cesare Mannelli
This study identifies VEGF-A released by astrocytes as a key mediator of chemotherapy-induced neuropathic pain and shows that the anti-VEGFR-1 mAb D16F7 alleviates this pain.
DOI 10.1101/2021.01.19.427244