Author

Luke Norton

The University of Texas at San Antonio Health Science CenterORCID 0000-0002-0231-5722Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Adelaide TovariD· 1 shared Anna‐Kaisa RuotsalaineniD· 1 shared Anna–Liisa LevoneniD· 1 shared Anne JacksoniD· 1 shared Annie A SmelteriD· 1 shared Arushi VarshneyiD· 1 shared Chao GaoiD· 1 shared Charles BurantiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperGenomics

Adelaide TovarORCID

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3 papers

Recent·Most cited

Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice

Juho Mononen, Mari Taipale, Marjo Malinen, Anna–Liisa Levonen, Anna‐Kaisa Ruotsalainen, Luke Norton, Sami Heikkinen

The paper investigates how genetic variation in two mouse strains affects chromatin accessibility and TF binding in adipose tissue, linking these changes to gene regulation and disease susceptibility.

bioRxiv · May 8, 2025 · PreprintGenetics

Sex-dependent adipose glucose partitioning by the mitochondrial pyruvate carrier

Chris E. Shannon, Terry M. Bakewell, Marcel J. Fourcaudot, Iriscilla Ayala, Annie A Smelter, Edgar A. Hinostroza, Giovanna Romero, Mara Asmis, Leandro Ceotto Freitas‐Lima, Martina Wallace, Luke Norton

This study investigates the role of the mitochondrial pyruvate carrier (MPC) in adipose glucose partitioning, finding sex-dependent effects on triglyceride synthesis and metabolic adaptation in mice.

Molecular Metabolism · Aug 11, 2024Peer-reviewedPhysiology

Population-scale skeletal muscle single-nucleus multi-omic profiling reveals extensive context specific genetic regulation

Arushi Varshney, Nandini Manickam, Peter Orchard, Adelaide Tovar, Christa Ventresca, Zhenhao Zhang, Fan Feng, Joseph Mears, Michael R. Erdos, Narisu Narisu, Kirsten Nishino, Vivek Rai, Heather M. Stringham, Anne Jackson, Tricia Tamsen, , Stephen C.J. Parker

The paper performs population-scale single-nucleus multi-omic profiling of skeletal muscle to identify genetic regulation across cell types and traits.

bioRxiv · Dec 15, 2023 · PreprintGenomics