Double crossed? Structural and computational studies of an unusual crosslinked heme in Methylococcus capsulatus cytochrome P460
Hans E. Pfalzgraf, Aditya G. Rao, Kakali Sen, Hannah R. Adams, Marcus J. Edwards, You Lü, Chin Weng Yong, Sofia Jaho, Takehiko Tosha, Hiroshi Sugimoto, Sam Horrell, James Beilsten‐Edmands, Robin Leslie Owen, Colin R. Andrew, Jonathan A. R. Worrall, , Thomas W. Keal
This study identifies a double crosslink between lysine and heme in Methylococcus capsulatus cytochrome P460 using structural biology and QM/MM simulations.
Chemical Science · Jan 1, 2025Peer-reviewedBiochemistry