Mohd Tayyab Adil

Gene Regulatory Network Reconfiguration in Direct Lineage Reprogramming

The paper uses CellOracle to analyze GRN reconfiguration during fibroblast to iEP reprogramming, identifying Fos and Yap1 as key factors for successful conversion.

Multiomic single-cell lineage tracing to dissect fate-specific gene regulatory programs

The paper introduces CellTag-multi, a method for multiomic single-cell lineage tracing that combines chromatin accessibility with lineage barcodes, and applies it to study reprogramming outcomes and gene regulatory programs in mouse hematopoiesis.

Understanding the basis of CYP26 mediated regulation of lens regeneration using ex vivo eye cultures and 4-oxo-RA

This study investigates the role of CYP26 in lens regeneration by testing the effects of 4-oxo-RA and CYP26 inhibition in Xenopus ex vivo cultures, finding that CYP26's function is not solely related to 4-oxo-RA generation or RA signaling.