PhysiologyJournal of Thrombosis and HaemostasisPeer-reviewed
A Mouse Model of the Protease Activated Receptor 4 (PAR4) Pro310Leu Variant has Reduced Platelet Reactivity
Han Xu, Elizabeth A. Knauss, Maria de la Fuente…·Marvin T. Nieman
This study creates a mouse model of the PAR4-P310L variant and shows reduced platelet reactivity to PAR4-activation peptide and thrombin, with no effect on ADP and convulxin responses.
12 citations