Bone marrow-derived macrophages loaded with boron carbide nanoparticles as selective boron carriers for crossing the blood-brain barrier toward the glioma microenvironment for boron neutron capture therapy
Anna Rudawska, Agnieszka Szczygieł, Katarzyna Węgierek‐Ciura, Jagoda Mierzejewska, Dawid Kozień, Paulina Żeliszewska, Monika Chaszczewska-Markowska, Piotr Rusiniak, Katarzyna Wątor, Zbigniew Pędzich, Elżbieta Pajtasz‐Piasecka, Bożena Szermer-Olearnik
This paper demonstrates that bone marrow-derived macrophages loaded with boron carbide nanoparticles can effectively deliver boron-10 across the blood-brain barrier to glioma cells, showing potential for boron neutron capture therapy.
bioRxiv · Jan 10, 2026 · PreprintCancer Biology