Physical interaction between MSL2 and CLAMP assures direct cooperativity and prevents competition at composite binding sites
Nikolas Eggers, Fotios Gkountromichos, Silke Krause, Aline Campos Sparr, Peter B. Becker
The paper investigates the cooperative binding of MSL2 and CLAMP to MREs on the X chromosome, showing that their physical interaction prevents competition and enhances affinity at composite binding sites.
bioRxiv · Apr 11, 2023 · PreprintMolecular Biology