Peter B. Becker

The paper shows that deletion of roX RNA in Drosophila male cells leads to X chromosome duplication to compensate for dosage imbalance, and full-length roX2 restores normal function.

This study reconstitutes Drosophila chromatin architecture in a cell-free system, revealing spontaneous formation of long-range interactions and TADs.

The paper investigates the interaction between Xbp1 and the DOM-A complex in Drosophila, revealing reciprocal targeting mechanisms and their roles in gene regulation and cell growth.

The paper determines the intrinsic substrate selectivity of the Drosophila Tip60 acetyltransferase complex using synthetic nucleosome arrays and identifies variable acetylation site effectiveness of an inhibitor.

This study identifies the Tip60 acetylome as a marker of the proliferative state in Drosophila, revealing its role in cell cycle regulation through histone and non-histone acetylation.

The paper investigates the context-dependent roles of three Drosophila methyltransferases in H3K36 methylation and their implications for chromatin reader interactions.

This study reveals how the dsRBD2 domain of the DExH-type helicase maleless orchestrates RNA unwinding through structural transitions, independent of ATP.

The paper investigates the cooperative binding of MSL2 and CLAMP to MREs on the X chromosome, showing that their physical interaction prevents competition and enhances affinity at composite binding sites.

This study identifies RUS, a lncRNA that promotes neurogenesis by regulating gene expression and epigenetic interactions during neuronal differentiation.

The paper identifies two DOMINO isoforms in Drosophila that form distinct complexes with different functions: DOM-B acts like SWR1 by depositing H2A.V, while DOM-A acts like NuA4 by acetylating H4K12.

The paper shows JASPer anchors JIL-1 to chromatin via H3K36me3 binding, forming a complex that regulates transcription and prevents heterochromatin formation in Drosophila.

The paper investigates how MSL2 and CLAMP cooperate to distinguish functional from non-functional MREs in Drosophila dosage compensation.

The paper introduces a method to measure nucleosome array regularity and spacing using nanopore sequencing, revealing relationships with chromatin states and promoter activity.

The paper identifies genome-wide phased nucleosome arrays in Drosophila, revealing a novel sequence motif and the role of the zinc finger protein Phaser in their formation.

This study shows that ACF1-containing chromatin remodeling complexes repress gene expression by maintaining a repressive chromatin state in Drosophila.

The paper investigates how the Drosophila dosage compensation complex activates X chromosome genes through chromosome looping within the active compartment.