Aline Campos Sparr

Dosage compensation defects due to roX RNA deletion are rescued by recalibration of X/autosome stoichiometry

The paper shows that deletion of roX RNA in Drosophila male cells leads to X chromosome duplication to compensate for dosage imbalance, and full-length roX2 restores normal function.

Self-organization of Drosophila chromatin architecture in a cell-free system

This study reconstitutes Drosophila chromatin architecture in a cell-free system, revealing spontaneous formation of long-range interactions and TADs.

The Tip60 acetylome is a hallmark of the proliferative state in Drosophila

This study identifies the Tip60 acetylome as a marker of the proliferative state in Drosophila, revealing its role in cell cycle regulation through histone and non-histone acetylation.

Physical interaction between MSL2 and CLAMP assures direct cooperativity and prevents competition at composite binding sites

The paper investigates the cooperative binding of MSL2 and CLAMP to MREs on the X chromosome, showing that their physical interaction prevents competition and enhances affinity at composite binding sites.

Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms

The paper identifies two DOMINO isoforms in Drosophila that form distinct complexes with different functions: DOM-B acts like SWR1 by depositing H2A.V, while DOM-A acts like NuA4 by acetylating H4K12.