Author

Zhuangli Yee

National University of SingaporeORCID 0000-0002-0257-5364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Barry B. HalliwelliD· 2 shared Jan GruberiD· 2 shared Lakshmi Narayanan LakshmananiD· 2 shared Rudiyanto GunawaniD· 2 shared Li Fang Ng· 1 shared

Activity by Year

2018-2018 · peak 2/yr

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5 top collaborators · 10 mutual co-author links

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2 shared papersGenetics

Barry B. HalliwellORCID

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2 papers

Recent·Most cited

GeneticsAging CellPeer-reviewedJul 24, 2018

Clonal expansion of mitochondrial DNA deletions is a private mechanism of ageing in long-lived animals

Lakshmi Narayanan Lakshmanan, Zhuangli Yee, Li Fang Ng…·Jan Gruber

The paper identifies mtDNA deletions in ageing nematodes and finds they are rare, not age-dependent, and not clonally expanded, suggesting they are not a major driver of ageing in short-lived species.

43 citations

C. elegansDNA methylation

𝕏 PostBluesky

Systems BiologybioRxivPreprintJan 27, 2018

Thermodynamic analysis of mitochondrial DNA breakpoints reveals mechanistic details of deletion mutagenesis

Lakshmi Narayanan Lakshmanan, Zhuangli Yee, Jan Gruber…·Rudiyanto Gunawan

The paper analyzes mtDNA deletion breakpoints using thermodynamic methods to identify misalignment lengths and proposes mechanisms for DSB-induced deletions.

3 citations

C. eleganshuman

𝕏 PostBluesky