Author

C.S. Biggs

University of WestminsterORCID 0000-0002-0268-4704Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Edward S. WicksteadiD· 2 shared Simon McArthuriD· 2 shared Stephen J. GettingiD· 2 shared Bradley ElliottiD· 1 shared Husnain A. Karim· 1 shared Roberta E. Manuel· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Edward S. WicksteadORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 9, 2020

Activation of the pro-resolving receptors Fpr2/3 attenuate lipopolysaccharide-induced inflammatory microglial activation

Edward S. Wickstead, Bradley Elliott, C.S. Biggs…·Simon McArthur

This study shows that activating Fpr2/3 receptors reduces LPS-induced inflammation in microglia by inhibiting NFκB and promoting resolution.

2 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceOxidative Medicine and Cellular LongevityPeer-reviewedJun 15, 2020

Reversal of β-amyloid induced microglial toxicity in vitro by activation of Fpr2/3

Edward S. Wickstead, Husnain A. Karim, Roberta E. Manuel…·Simon McArthur

This study shows that activating Fpr2 with QC1 reverses β-amyloid-induced microglial toxicity in vitro by reducing ROS production and metabolic shifts.

20 citations

mousebulk RNA-seq

𝕏 PostBluesky