NeuroscienceAdvanced SciencePeer-reviewed
Micromotion derived fluid shear stress mediates peri-electrode gliosis through mechanosensitive ion channels
Alexandre Trotier, Enrico Bagnoli, Tomasz Walski…·Manus Jonathan Paul Biggs
This paper shows that fluid shear stress from micromotion around neural implants triggers gliosis via mechanosensitive ion channels, and modulating PIEZO1 affects astrocyte reactivity.
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