Manus Jonathan Paul Biggs

This study generates cardiac resident-like macrophages and cardiomyocytes from iPSCs to investigate their interactions in 2D and 3D settings, showing improved cardiomyocyte maturation and function when co-cultured.

This study evaluates a citrate-based composite material for orthopedic applications, showing it supports cell growth and osteogenic activity in vitro and promotes tissue regeneration in vivo.

This paper shows that fluid shear stress from micromotion around neural implants triggers gliosis via mechanosensitive ion channels, and modulating PIEZO1 affects astrocyte reactivity.