Author

Faviolla A. Báez-Cruz

University of PennsylvaniaORCID 0000-0002-0312-870XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Donald A. WinkelmanniD· 2 shared E. Michael OstapiD· 2 shared Robert C. CailiD· 2 shared Yale E. GoldmaniD· 2 shared Bipasha BaruaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

Donald A. WinkelmannORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedDec 24, 2025

A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment

Robert C. Cail, Bipasha Barua, Faviolla A. Báez-Cruz…·E. Michael Ostap

This paper investigates the HCM mutation M493I in β-cardiac myosin, showing it disrupts the super-relaxed state, slows ADP release, and enhances actin attachment and force production, leading to hypercontractility.

9 citationstop 3%

humanexperimental assay

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BiochemistryJournal of Biological ChemistryPeer-reviewedMar 19, 2025

Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states

Robert C. Cail, Faviolla A. Báez-Cruz, Donald A. Winkelmann…·E. Michael Ostap

This study investigates the dynamics between the super-relaxed (SRX) and disordered-relaxed (DRX) states of β-cardiac myosin, showing they are in rapid equilibrium and how mutations and inhibitors affect this balance.

21 citationstop 1%

experimental assay

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