Pharmacology & ToxicologybioRxivPreprint
Structural Dynamics of the Dopamine D2 Receptor with a Non-Basic Ligand
Qinxin Sun, Guodong He, Damian Bartuzi…·Agnieszka Anna Kaczor
The paper presents a cryo-EM structure of the dopamine D2 receptor bound to a non-basic ligand, revealing structural dynamics and binding energy landscapes that explain subtype selectivity.