A tumor suppressor role of the miR-15b/16-2 cluster in T-cell acute lymphoblastic leukemia
Sara González-García, María Jesús García-León, Marina García-Peydró, Patricia Fuentes, Juan Alcaín, Enrique Martín‐Gayo, Carlo Maria Croce, Ramiro Garzon, Marı́a L. Toribio
This study identifies miR-15b/16-2 as tumor suppressors in T-cell acute lymphoblastic leukemia by showing their role in inhibiting proliferation and promoting apoptosis through repression of BCL-2 and CYCLIN D3.
bioRxiv · Jul 7, 2025 · PreprintImmunology