BiochemistryCell ResearchPeer-reviewed
Molecular basis of vitamin K-dependent protein γ-glutamyl carboxylation
Qihang Zhong, Dandan Chen, Jinkun Xu…·Jing Hang
This study reports cryo-EM structures of GGCX bound to VKDPs and vitamin K, revealing its dual-catalytic mechanism and disease-associated mutation clusters.
5 citations