Author

Dandan Chen

Peking UniversityORCID 0000-0003-4056-7709Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Dandan Chen1 paper · Sir Run Run Shaw Hospital

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Caihong YuniD· 1 shared Chenmin GuoiD· 1 shared Chunli SongiD· 1 shared Guopeng WangiD· 1 shared Jie QiaoiD· 1 shared Jing HangiD· 1 shared Jinkun XuiD· 1 shared Jun CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Caihong YunORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJun 3, 2026

A phage-encoded small RNA that mimics chimeric guide to inhibit CRISPR-Cas9

Yuehua Chen, Peng Zhao, Chenmin Guo…·Liang Liu

The paper identifies a phage-encoded small RNA that mimics the CRISPR-Cas9 guide RNA to inhibit the system and demonstrates its reprogrammability for DNA cleavage and trans-cleavage.

DOI 10.64898/2026.06.03.729762

experimental assay

𝕏 PostBluesky

BiochemistryCell ResearchPeer-reviewedSep 29, 2025

Molecular basis of vitamin K-dependent protein γ-glutamyl carboxylation

Qihang Zhong, Dandan Chen, Jinkun Xu…·Jing Hang

This study reports cryo-EM structures of GGCX bound to VKDPs and vitamin K, revealing its dual-catalytic mechanism and disease-associated mutation clusters.

5 citations

humanstructural biology

𝕏 PostBluesky