MyD88-dependent signaling promotes smooth muscle cell phenotypic modulation and fibrous cap formation in murine atherosclerosis
Stine Gunnersen, Julián Albarrán-Juárez, Lise Filt Jensen, Jeong Tangkjær Shim, Charlotte Brandt Sørensen, Jacob Fog Bentzon
This study shows that MyD88 promotes smooth muscle cell phenotypic modulation and fibrous cap formation in atherosclerosis by reducing cap SMC recruitment and preserving contractile phenotype.
bioRxiv · Jul 1, 2025 · PreprintPathology