Radha Kalluri

Genetic Targeting and Conductance-Based Modeling Reveal Novel Diversity Within Mouse Type II Spiral Ganglion Neurons

This study identifies biophysical and ion channel diversity in mouse type II spiral ganglion neurons using genetic tools and computational modeling, revealing distinct subtypes with potential functional differences.

Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

This study develops a virus-free, inducible system to generate human inner ear hair cell-like cells from iPS cells, achieving higher efficiency and faster conversion than viral methods.

Vestibular afferent neurons develop normally in the absence of quantal/glutamatergic input

This study shows that vestibular ganglion neurons develop normal biophysical diversity without glutamatergic input, but with subtle differences in large cells.

Muscarinic acetylcholine receptors modulate HCN channel properties in vestibular ganglion neurons

This study shows that muscarinic signaling modulates HCN channel properties in vestibular ganglion neurons, increasing current availability and altering voltage activation range.

The onset of hearing triggers nuclear translocation in inner hair cells

The paper reports a programmed nuclear translocation in rat cochlear inner hair cells coinciding with the onset of hearing and functional maturation.