Mehul Dattani

This study analyzes transcriptomic differences between 46,XY and 46,XX human fetal brain cortex samples to understand sex chromosome and hormone effects during early development.

This study maps the anatomical and transcriptional changes in human fetal ovaries during development using single-nuclei RNA sequencing and other techniques, identifying novel pathways and regulators.

This study identifies a recessive PRDM13 mutation causing congenital hypogonadotropic hypogonadism and cerebellar hypoplasia through mouse models and human expression analysis.

This study shows that THRA mutations impair neural progenitor cell proliferation and organisation in human cortical development using patient-derived iPSCs.