Theodoros Xenakis

This study identifies three leukaemia stem cell subtypes in paediatric AML and shows that combining CLEC12A and CD84 targets all subtypes while sparing healthy cells.

The paper evaluates single cell transcriptomic methods on challenging placental tissue, finding that sample processing and storage have greater impact on results than technical variations.

This study compares in vivo and in vitro midbrain development to assess their similarity to human fetal tissue.

This study identifies spatially distinct fetal and maternal cell contributions to severe preeclampsia, highlighting new maternal immune signatures and potential therapeutic targets.

This study compares molecular and cellular signatures of Parkinson's disease and Parkinson's disease with dementia using single-nuclear transcriptomics, finding distinct gene expression patterns and biological pathways.

This paper investigates VEGF supplementation as a treatment for congenital diaphragmatic hernia (CDH)-associated lung abnormalities using an ex vivo model and nanoparticle-based delivery in vivo.

This study uses single-nucleus and bulk RNA sequencing to identify novel pathogenic mechanisms of ovarian insufficiency in Turner Syndrome, beyond X chromosome haploinsufficiency.

This study maps the anatomical and transcriptional changes in human fetal ovaries during development using single-nuclei RNA sequencing and other techniques, identifying novel pathways and regulators.