Single-Molecule Imaging Reveals Differential Stability of Alpha-Synuclein Aggregates
Shih-Chin Wang, Stephanie J. Zhang, Tal Gilboa, John Kang, Anastasia Kuzkina, George T. Kannarkat, Liangxiao Chen, William M. Shih, Alice S. Chen‐Plotkin, Vikram Khurana, David R. Walt
This study uses single-molecule imaging to show that Parkinson's disease-associated alpha-synuclein aggregates are more stable than physiological multimers under dilution.
bioRxiv · Jul 4, 2026 · PreprintNeuroscience