Author

Lisa Hahnefeld

Goethe University FrankfurtORCID 0000-0002-0382-5695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:metabolomics· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Irmgard TegederiD· 2 shared Luisa FranckiD· 2 shared Marc-Philipp WeyeriD· 2 shared Robert GurkeiD· 2 shared Carlo AngioniiD· 1 shared Chloe M. HalliD· 1 shared Clara A. SimacekiD· 1 shared Florian MolnariD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Irmgard TegederORCID

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3 papers

Recent·Most cited

BioinformaticsBriefings in BioinformaticsPeer-reviewedJul 1, 2026

LipiDetective - a deep learning model for the identification of molecular lipid species in tandem mass spectra

Vivian Würf, Nikolai Köhler, Florian Molnar…·Josch Konstantin Pauling

LipiDetective is a transformer model that accurately identifies molecular lipid species in tandem mass spectra using learned fragmentation patterns, improving comparability across experiments.

DOI 10.1093/bib/bbag378

metabolomicstransformer / foundation model

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 20, 2026

Nerve injury triggers nociceptive hypersensitivity with interhemispheric divergence in haplodeficient GAD67-GFP mice

Johannes Spahn, Clara A. Simacek, Lisa Hahnefeld…·Irmgard Tegeder

This study shows that GAD67-GFP mice with GABA deficiency develop thermal allodynia after nerve injury, while wildtype mice do not, indicating GABA's role in neuropathic pain.

DOI 10.64898/2026.05.17.725734

mouseelectronic health records

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 21, 2026

Temporary deterioration of health and behavior during pexidartinib-mediated microglia depletion and repopulation in progranulin-deficient mice

Marc-Philipp Weyer, Lisa Hahnefeld, Luisa Franck…·Irmgard Tegeder

This study shows that microglia depletion in progranulin-deficient mice causes temporary health and behavioral deterioration, with lasting proinflammatory effects in the brain.

DOI 10.64898/2026.04.20.719642

mousebulk RNA-seq

𝕏 PostBluesky