BiochemistryJournal of Medicinal ChemistryPeer-reviewed
Synthesis of pyrazole-based macrocycles leads to a highly selective inhibitor for MST3
Jennifer Alisa Amrhein, Lena M. Berger, Dimitrios-Ilias Balourdas…·Thomas Hanke
The paper designs and synthesizes a macrocyclic inhibitor, JA310, that selectively targets MST3 with high potency and kinome-wide selectivity.