Author
Goethe University FrankfurtORCID 0000-0002-1232-0138Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Dmitri Segal, Lisa Kainacher, Timo Muffel…·Georg E. Winter
This paper introduces TRIPs, neomorphic molecules that recruit BAF complexes to rewire BCL6 in DLBCL, inducing apoptosis through chromatin remodeling.
Xiaoyun Wang, Jianxian Sun, Shabbir Ahmad…·Levon Halabelian
This study introduces E-ASMS, a method to detect weak binders and assess enantioselectivity, identifying 16 binders across 12 human protein targets with confirmed binding mechanisms.
Joshua Gerninghaus, Rezart Zhubi, Andreas Krämer…·Thomas Hanke
The paper optimizes a 2-aminopyrimidine-based macrocycle to create a dual EPHA2/GAK kinase inhibitor with antiviral activity against dengue virus.