Gerald A. Higgins

This study quantifies 4D nuclear morphology changes in human astrocytes treated with valproic acid, showing significant size and shape differences by day 7.

The paper develops a 3D morphometric analysis pipeline for cell nuclei and nucleoli, achieving high classification accuracy in prostate cancer and fibroblast cells.

The paper introduces a 3D cell nuclear morphology dataset and evaluates classification algorithms using voxel-based morphometric measures.

The paper investigates parental allele-specific genome architecture and transcription dynamics during the cell cycle in lymphoblastoid cells, identifying allele-biased expression and chromatin organization features.