Paul L. Greer

This study shows that combining RNAi to silence MSH3 and HTT reduces huntingtin inclusions and restores gene expression in HD mice.

The paper shows that silencing SOD1 with optimized di-siRNA extends survival and prevents disease progression in ALS mice.

The paper identifies neurexin gene expression patterns in olfactory sensory neurons that guide axonal targeting to specific glomeruli through interactions with neuroligins in mitral/tufted cells.