Cheng Peng

The paper identifies a stress-response program in mid-zone hepatocytes during early acute liver injury that suppresses proliferation via the Atf4-Chop-Btg2 axis.

This study identifies the C9orf72/SMCR8 complex as essential for microglial lysosomal repair and homeostasis, revealing its role in preventing neuroinflammation through RAB8A-ESCRT pathways.

This study identifies Chi3l1 as a metabolic regulator that differentially affects hepatic macrophage fate in MASLD by modulating glucose metabolism in Kupffer cells.

CopyKit is a computational tool that resolves clonal substructure and reconstructs genetic lineages in tumors using single cell copy number data.