Author

Jia He

Yunnan UniversityORCID 0009-0007-4616-7091Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Jia He3 papers · Chongqing Medical University

Biology Disciplines

Click to filter author papers

Pathology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Zhao ShaniD· 3 shared Bo CheniD· 2 shared Cheng PengiD· 2 shared Cheng XieiD· 2 shared Chengxiang Deng· 2 shared Keqin Wang· 2 shared Weiju Lu· 2 shared Xiane Zhu· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPharmacology & Toxicology

Zhao ShanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologyeLifePeer-reviewedOct 26, 2026

Mid-zone hepatocytes trade proliferation for survival via Atf4-Chop axis in early acute liver injury

Yaying Zhu, Chengxiang Deng, Bo Chen…·Zhao Shan

The paper identifies a stress-response program in mid-zone hepatocytes during early acute liver injury that suppresses proliferation via the Atf4-Chop-Btg2 axis.

DOI 10.7554/elife.108646.4

mousespatial transcriptomics

𝕏 PostBluesky

PathologyeLifePeer-reviewedMay 11, 2026

Hyperactivated Glycolysis Drives Spatially-Patterned Kupffer Cell Depletion in MASLD

Jia He, Ran Li, Cheng Xie…·Zhao Shan

This study identifies hyperactivated glycolysis as a driver of spatially-patterned Kupffer cell depletion in MASLD, suggesting glucose metabolism as a therapeutic target.

2 citations

mousemetabolomics

𝕏 PostBluesky

PhysiologybioRxivPreprintMay 6, 2025

Differential Regulation of Hepatic Macrophage Fate by Chi3l1 in MASLD

Jia He, Bo Chen, Weiju Lu…·Zhao Shan

This study identifies Chi3l1 as a metabolic regulator that differentially affects hepatic macrophage fate in MASLD by modulating glucose metabolism in Kupffer cells.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky