SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif
Joshua J. Hamey, Manan Shah, John D. Wade, Tara K. Bartolec, Richard E.H. Wettenhall, Kate G R Quinlan, Nicholas A. Williamson, Marc Ronald Wilkins
The paper identifies SMYD5 as a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through a KXY motif, showing its distinct substrate specificity from histone substrates.
bioRxiv · Oct 10, 2024 · PreprintMolecular Biology