Marc Ronald Wilkins

The paper shows that alternative splicing patterns are more specific to cell identity than gene expression and are sparsely distributed across cell types.

The paper identifies SMYD5 as a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through a KXY motif, showing its distinct substrate specificity from histone substrates.

This paper introduces HyperG-VAE, a Bayesian deep generative model for GRN inference using scRNA-seq data, showing effectiveness in clustering, visualization, and revealing gene regulation patterns.

The paper presents a comprehensive human transcriptome atlas with single-nucleotide resolution, identifying thousands of novel RNA species and regulatory interactions.