Author

Tara K. Bartolec

European Molecular Biology LaboratoryORCID 0000-0002-5291-6972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Alessio Ling Jie YangiD· 1 shared Alexandra KoumoutsiiD· 1 shared Anthony J. CesareiD· 1 shared Athanasios TypasiD· 1 shared Clément M. PoteliD· 1 shared David Van Ly· 1 shared Federico CoronaiD· 1 shared Georgia Rose KaferiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Alessio Ling Jie YangORCID

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3 papers

Recent·Most cited

Pervasive phosphorylation by phage T7 kinase disarms bacterial defenses

Tara K. Bartolec, Karin Mitosch, Clément M. Potel, Federico Corona, Alessio Ling Jie Yang, Nicolai Karcher, Mira Lea Burtscher, Alexandra Koumoutsi, Isabelle Becher, Lena Sarah Müller, Jacob Bobonis, Manjeet Kumar, Marco Galardini, Athanasios Typas, Mikhail M. Savitski

This study reveals that phage T7 kinase broadly phosphorylates host and phage proteins, disabling bacterial defense systems through widespread phosphorylation.

Nature · Aug 19, 2026Peer-reviewedMicrobiology

SMYD5 is a ribosomal methyltransferase which trimethylates RPL40 lysine 22 through recognition of a KXY motif

Joshua J. Hamey, Manan Shah, John D. Wade, Tara K. Bartolec, Richard E.H. Wettenhall, Kate G R Quinlan, Nicholas A. Williamson, Marc Ronald Wilkins

The paper identifies SMYD5 as a ribosomal methyltransferase that trimethylates RPL40 lysine 22 through a KXY motif, showing its distinct substrate specificity from histone substrates.

bioRxiv · Oct 10, 2024 · PreprintMolecular Biology

Telomere-loop dynamics in chromosome end protection

David Van Ly, Ronnie Ren Jie Low, Sonja Frölich, Tara K. Bartolec, Georgia Rose Kafer, Hilda A. Pickett, Katharina Gaus, Anthony J. Cesare

The paper investigates telomere-loop dynamics in chromosome end protection using super-resolution microscopy and finds that t-loops act as conformational switches regulating ATM activation independent of telomere fusion.

Molecular Cell · Jul 20, 2018Peer-reviewedMolecular Biology