Author

Nissa J. Larson

Purdue University West LafayetteORCID 0000-0002-0466-3966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:human· 1 Approach:optimal transport· 1 Organism:zebrafish· 1

Frequent Co-Authors

David M. UmulisiD· 2 shared Linlin LiiD· 2 shared Aasakiran MadamanchiiD· 1 shared Donny Hanjaya‐PutraiD· 1 shared Gregory T. ReevesiD· 1 shared Jayden KamiD· 1 shared Jeremiah J. ZartmaniD· 1 shared Razeen ShaikhiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersDevelopmental Biology

David M. UmulisORCID

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2 papers

Recent·Most cited

Developmental Biologynpj Systems Biology and ApplicationsPeer-reviewedSep 28, 2026

Stochastic Modeling of BMP Heterodimer-Receptor Interactions Shows Emergence of Low-Pass Filtering Behavior

Nissa J. Larson, Aasakiran Madamanchi, Linlin Li, David M. Umulis

The paper develops a stochastic model of BMP receptor interactions to show the heterodimer-heterotetramer complex functions as a low-pass filter in zebrafish dorsoventral axis formation.

DOI 10.1038/s41540-026-00825-w

zebrafishstatistical model

𝕏 PostBluesky

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedSep 14, 2024

Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway

Razeen Shaikh, Nissa J. Larson, Jayden Kam…·Gregory T. Reeves

The paper examines how the BMP-Smad pathway balances trade-offs among response speed, noise amplification, and sensitivity to receptor input by tuning non-conserved parameters.

8 citations

humanstatistical model

𝕏 PostBluesky