Jeremiah J. Zartman

This paper demonstrates that sodium-calcium cross-talk regulates calcium oscillations in endothelial cells, which control angiogenic signaling and can be manipulated to generate angiogenic responses in engineered tissues.

CalciumInsights provides a user-friendly tool for analyzing calcium signals across multiple organisms and tissues without requiring programming expertise.

This study uses optogenetics to control organ growth in Drosophila by manipulating calcium signaling, revealing how light intensity and timing affect organ size and tumor morphology.

The paper examines how the BMP-Smad pathway balances trade-offs among response speed, noise amplification, and sensitivity to receptor input by tuning non-conserved parameters.

The paper develops a Bayesian optimization framework to reverse-engineer morphogenesis by calibrating physics-based models to match experimental imaging data of Drosophila wing imaginal discs.

This study shows Piezo channels regulate epithelial topology and organ size by modulating cell proliferation, apoptosis, and extrusion through calcium and Rho signaling.

This study investigates how Gq regulates wing development in Drosophila by affecting Ca2+ signaling and growth pathways, showing both Ca2+-dependent and -independent mechanisms.

The paper investigates how cytoskeletal regulation and proliferation are coordinated during Drosophila wing disc development to balance tissue growth and shape.

This study screens GPCRs and G proteins in Drosophila to identify those involved in epithelial morphogenesis, finding several with severe phenotypes and disease relevance.

This paper identifies two cell populations with distinct Ca2+ signaling dynamics and shows how hormonal signals and gap junction communication regulate organ size.

MAPPER identifies differential regulation of Drosophila wing features through automated image analysis, revealing scaling patterns and the role of Piezo in bilateral symmetry.

This study investigates the in vivo role of intercellular calcium signaling in Drosophila wing development, showing its impact on wing morphology and patterning through chemical stimuli and extracellular matrix interactions.

The paper develops a neural-network-based method to analyze intercellular calcium oscillations in Drosophila wing discs and shows that Hedgehog morphogen controls their frequency and spatial patterning.

QuickStitch corrects vignetting in confocal mosaics through recursive normalization, enabling seamless stitching of large immunofluorescence images without visible seams.

The paper introduces a chip-based system to study mechanical stress and biochemical signaling in micro-organs, identifying conditions for intercellular calcium waves in Drosophila wing discs.

This paper develops a computational model to study size control in Drosophila embryonic tissues, showing that passive mechanical forces can explain size regulation but require patterning for asymmetries in cell death.