Author

Melissa A R Rolfes

Centers for Disease Control and PreventionORCID 0000-0002-0483-9941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Adam S. LauringiD· 2 shared Alexandra M. MellisiD· 2 shared Carlos Gabriel GrijalvaiD· 2 shared Emily E. BendalliD· 2 shared Emily Toth MartiniD· 2 shared H. Keipp TalbotiD· 2 shared Natasha HalasaiD· 2 shared William J. FitzsimmonsiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Adam S. LauringORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedApr 28, 2025

In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants

Emily E. Bendall, Derek E. Dimcheff, Leigh Papalambros…·Adam S. Lauring

This study uses longitudinal sequencing of a household cohort to analyze within-host SARS-CoV-2 dynamics, finding rare positive selection in spike and genetic hitchhiking between synonymous and nonsynonymous variants.

3 citations

humanwhole-genome sequencing

𝕏 PostBluesky

MicrobiologyVirus EvolutionPeer-reviewedJan 1, 2024

Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons

Emily E. Bendall, Yuwei Zhu, William J. Fitzsimmons…·Adam S. Lauring

This study analyzes within-host influenza A virus evolution in a household cohort over three seasons, finding purifying selection and rare positive selection.

13 citations

humanwhole-genome sequencing

𝕏 PostBluesky