Author

Carlos G. Grijalva

Vanderbilt University Medical CenterORCID 0000-0002-2329-7797Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Adam S. LauringiD· 2 shared Alexandra M. MellisiD· 2 shared Emily E. BendalliD· 2 shared Emily Toth MartiniD· 2 shared H. Keipp TalbotiD· 2 shared Melissa A R RolfesiD· 2 shared Natasha HalasaiD· 2 shared William J. FitzsimmonsiD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Adam S. LauringORCID

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2 papers

Recent·Most cited

In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants

Emily E. Bendall, Derek E. Dimcheff, Leigh Papalambros, William J. Fitzsimmons, Yuwei Zhu, Jonathan Schmitz, Natasha Halasa, James D. Chappell, Emily Toth Martin, Jessica E. Deyoe, Sarah E. Smith-Jeffcoat, Melissa A R Rolfes, Alexandra M. Mellis, H. Keipp Talbot, Carlos Gabriel Grijalva, Adam S. Lauring

This study uses longitudinal sequencing of a household cohort to analyze within-host SARS-CoV-2 dynamics, finding rare positive selection in spike and genetic hitchhiking between synonymous and nonsynonymous variants.

PLoS Pathogens · Apr 28, 2025Peer-reviewedMicrobiology

Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons

Emily E. Bendall, Yuwei Zhu, William J. Fitzsimmons, Melissa A R Rolfes, Alexandra M. Mellis, Natasha Halasa, Emily Toth Martin, Carlos G. Grijalva, H. Keipp Talbot, Adam S. Lauring

This study analyzes within-host influenza A virus evolution in a household cohort over three seasons, finding purifying selection and rare positive selection.

Virus Evolution · Jan 1, 2024Peer-reviewedMicrobiology