Adam S. Lauring

H5N5 virus transmission is driven by repeated cross-Atlantic introductions and transmission among high latitude seabirds

This study shows H5N5 viruses have been repeatedly introduced across the Atlantic by high latitude seabirds, with more frequent introductions in fall and spring, and a distinct ecology from H5N1.

Host genotype and sex shape influenza evolution and defective viral genomes

The paper shows host genotype and sex influence influenza virus evolution and defective genome formation through experimental adaptation and structural analysis.

Mutation rate variability in viral populations: implications for lethal mutagenesis

This paper shows that mutation rate variability in influenza A virus affects lethal mutagenesis models, suggesting gamma-Poisson distributions are more accurate than Poisson models for predicting viral extinction.

Surveillance on California dairy farms reveals multiple possible sources of H5N1 transmission

The paper investigates H5N1 transmission on dairy farms by sampling air, wastewater, and milk, finding infectious virus in air and wastewater, viral RNA in cow breath, and subclinical infections in cows.

HAVEN: Hierarchical Attention for Viral protEin-based host iNference

HAVEN predicts viral hosts from protein sequences, achieving high accuracy for both common and rare hosts while outperforming larger models.

In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants

This study uses longitudinal sequencing of a household cohort to analyze within-host SARS-CoV-2 dynamics, finding rare positive selection in spike and genetic hitchhiking between synonymous and nonsynonymous variants.

Surveillance of H5 HPAI in Michigan using retail milk

This study uses milk samples from Michigan markets to detect H5N1 avian influenza virus, finding two positive samples suggesting potential HPAI spread in dairy herds.

Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons

This study analyzes within-host influenza A virus evolution in a household cohort over three seasons, finding purifying selection and rare positive selection.