Author

Leigh Papalambros

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Adam S. LauringiD· 2 shared William J. FitzsimmonsiD· 2 shared Alexa D. Simulynas· 1 shared Alexander L. GreningeriD· 1 shared Alexandra M. MellisiD· 1 shared Alvin Crespo Bellido· 1 shared Carlos Gabriel GrijalvaiD· 1 shared Clara R. MalekshahiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersEvolutionary Biology

Adam S. LauringORCID

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2 papers

Recent·Most cited

H5N5 virus transmission is driven by repeated cross-Atlantic introductions and transmission among high latitude seabirds

Clara R. Malekshahi, Nicole St. Clair Knobloch, Alvin Crespo Bellido, Alexa D. Simulynas, Stephanie Goya, Leigh Papalambros, William J. Fitzsimmons, Alexander L. Greninger, Adam S. Lauring, Jonathan A. Runstadler, Martha I. Nelson, Wendy Blay Puryear, Louise H. Moncla

This study shows H5N5 viruses have been repeatedly introduced across the Atlantic by high latitude seabirds, with more frequent introductions in fall and spring, and a distinct ecology from H5N1.

bioRxiv · Oct 31, 2026 · PreprintEvolutionary Biology

In depth sequencing of a serially sampled household cohort reveals the within-host dynamics of Omicron SARS-CoV-2 and rare selection of novel spike variants

Emily E. Bendall, Derek E. Dimcheff, Leigh Papalambros, William J. Fitzsimmons, Yuwei Zhu, Jonathan Schmitz, Natasha Halasa, James D. Chappell, Emily Toth Martin, Jessica E. Deyoe, Sarah E. Smith-Jeffcoat, Melissa A R Rolfes, Alexandra M. Mellis, H. Keipp Talbot, Carlos Gabriel Grijalva, Adam S. Lauring

This study uses longitudinal sequencing of a household cohort to analyze within-host SARS-CoV-2 dynamics, finding rare positive selection in spike and genetic hitchhiking between synonymous and nonsynonymous variants.

PLoS Pathogens · Apr 28, 2025Peer-reviewedMicrobiology