Mira Han

The paper shows that fasting disrupts the TGF-β-InsP6-HDAC3 axis, inducing ER stress and eliminating DNA-damaged cells to maintain tissue quality.

The paper shows that phytic acid activates the HDAC3 epigenetic axis to maintain intestinal barrier function, with therapeutic potential in inflammatory bowel disease.

The paper introduces a splicing graph to compare exon-based and splice junction-based alternative splicing detection methods, revealing discrepancies and integrating results.

The paper integrates chromatin states and Micro-C contacts to identify chromatin interaction signatures across cell types, revealing dynamic patterns of chromatin conformation.

The paper uses machine learning on enhancer perturbation data to identify a new class of enhancers that drive transcription without strong promoter contact.

The paper analyzes TE transcript variation across non-tumorous tissues and identifies co-expression modules with immune genes and KZFPs.

This study evaluates the mappability of transposable elements in the human genome using paired-end read libraries of varying lengths, showing increasing unique mappability with longer reads.