Author

Nguyen Tran

University of Nevada, Las VegasPrimary ORCID profile (0000-0002-2746-4193 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Nguyen TraniD1 paper · Drexel University

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Prasun GuhaiD· 4 shared Henning Jacob JesseniD· 3 shared Kevin RitteriD· 3 shared Loretta Viera Preval· 3 shared Zachary SiniD· 3 shared Anas K. Gremida· 2 shared Anuj Shukla· 2 shared George Koshkaryan· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

Prasun GuhaORCID

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4 papers

Recent·Most cited

Fasting disrupts the InsP6 HDAC3 axis to drive ER stress-mediated clearance of DNA-damaged cells and enforce tissue quality control.

Sujan Chetterjee, Zachary Sin, Richard Van, Nguyen Tran, Tam Tran, Anuj Shukla, Lucile M. Jeusset, George Koshkaryan, Kevin Saldana, Rayan Muneer, Loretta Viera Preval, Lingkun Gu, Faizan Bhat, Kevin Ritter, Katherine Huang, , Prasun Guha

The paper shows that fasting disrupts the TGF-β-InsP6-HDAC3 axis, inducing ER stress and eliminating DNA-damaged cells to maintain tissue quality.

bioRxiv · May 27, 2026 · PreprintCell Biology

Phytic Acid (InsP6) Activates HDAC3 Epigenetic Axis to Maintain Intestinal Barrier Function

Sujan Chatterjee, Zachary Sin, Nguyen Tran, Loretta Viera Preval, Anuj Shukla, Tam Tran, George Koshkaryan, Kevin Ritter, Xue Bessie Su, Saharat Jolak Ragsac, Seungman Park, Qian Liu, Richard Van, Katherine Huang, Kayci Huff-Hardy, , Prasun Guha

The paper shows that phytic acid activates the HDAC3 epigenetic axis to maintain intestinal barrier function, with therapeutic potential in inflammatory bowel disease.

Nature Communications · Feb 9, 2026Peer-reviewedCell Biology

βA3/A1-crystallin is an epigenetic regulator of histone deacetylase 3 (HDAC3) in the retinal pigmented epithelial (RPE) cells

Sujan Chatterjee, Sayan Ghosh, Zachary Sin, Vishnu Suresh Babu, Loretta Viera Preval, Emily Davis, Nguyen Tran, Sridhar Bammidi, Pooja Gautam, Stacey Hose, Yuri V. Sergeev, Miguel Flores‐Bellver, Kevin Ritter, Henning Jacob Jessen, Issam Aldiri, , Prasun Guha

The paper identifies βA3/A1-crystallin as an epigenetic regulator of HDAC3 in RPE cells, showing it enhances HDAC3 activity through CK2 interaction and InsP6 regulation, linking it to AMD pathogenesis.

Aging Cell · Jul 15, 2025Peer-reviewedCell Biology

Reengineering mRNA lipid nanoparticles for systemic delivery to pancreas

Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, Dong Soo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya

This study develops lipid nanoparticles with vitamin D3 to achieve selective pancreatic delivery of mRNA, showing high efficacy and low toxicity.

Advanced Materials · Jun 12, 2025Peer-reviewedBioengineering