Author

Yoshinori Kobayashi

Kitasato UniversityORCID 0000-0002-4289-7392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Akiko Maruko· 2 shared Kenshiro OshimaiD· 2 shared Norihiro OkadaiD· 2 shared Akino Wakasugi· 1 shared Akinori NishiiD· 1 shared Eiko MoriiD· 1 shared Hiroshi OdaguchiiD· 1 shared Mariko SekineiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Akiko Maruko

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2 papers

Recent·Most cited

Intron retention can be an excellent marker for evaluating the depressed state and useful for discovering new pathways in the recovery of depression by a drug.

Norihiro Okada, Kenshiro Oshima, Akiko Maruko, Mariko Sekine, Naoki Ito, Akino Wakasugi, Eiko Mori, Hiroshi Odaguchi, Yoshinori Kobayashi

The paper identifies intron retention (IR) as a biomarker for depression and shows its utility in discovering recovery pathways through RNA-seq analysis of peripheral blood mononuclear cells.

Frontiers in Psychiatry · Sep 19, 2024Peer-reviewedGenetic & Genomic Medicine

A potential pathway that links intron retention with the physiological recovery by a Japanese herbal medicine

Norihiro Okada, Kenshiro Oshima, Akiko Maruko, Trieu-Duc Vu, Ming-Tzu Chiu, Mitsue Nishiyama, Masahiro Yamamoto, Akinori Nishi, Yoshinori Kobayashi

The paper investigates how Juzentaihoto (JTT) reduces intron retention in klotho mice by activating AMPK signaling, linking it to metabolic changes and physiological recovery.

bioRxiv · Dec 2, 2023 · PreprintBioinformatics