Christina Begon‐Pescia

Temporal dynamics of macrophages transcriptional profiles during zebrafish wound healing

This study uses bulk RNA sequencing to analyze zebrafish macrophage transcriptional changes during wound healing, revealing dynamic shifts in functional states over time.

Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation and transcriptional regulation as human S100 proteins

The paper characterizes two teleost-specific S100 proteins, S100i1 and S100i2, showing they share structural, functional, and expression features with mammalian S100 proteins.

During an inflammatory response, zebrafish tnfa and tnfb are expressed by different cell types and have distinct expression kinetics

The paper tracks tnfb expression in zebrafish using reporter lines and scRNAseq, showing distinct kinetics and cell-type-specific expression compared to tnfa and il1b.