Catherine Birck

The paper identifies two compounds that target GPX4 and TXNRD1 to induce apoptosis and ferroptosis in AML cells, effectively eradicating malignant cells while sparing normal hematopoietic cells.

This study identifies GSK3 as the kinase responsible for phosphorylating STARD3, which regulates ER-LE/Lys contacts and endosome positioning through a phosphorylation switch.

The paper characterizes two teleost-specific S100 proteins, S100i1 and S100i2, showing they share structural, functional, and expression features with mammalian S100 proteins.

This study reveals the structure and mechanism of Leptin-mediated LEP-R assembly, showing a 3:3 stoichiometry and highlighting the role of Leptin restructuring in activating signaling.

This study maps NEUROG3 occupancy in human pancreatic endocrine progenitors, identifying 1268 target genes and linking NEUROG3 to islet cell development and type 2 diabetes risk variants.