Author

Sylwia D. Tyrkalska

Instituto de Salud Carlos IIIORCID 0000-0001-6654-0163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Víctoriano MuleroiD· 3 shared Diana García‐MorenoiD· 2 shared Juan M. Lozano GiliD· 2 shared Mai Nguyen ChiiD· 2 shared Alicia Martínez‐LópeziD· 1 shared Andrés JereziD· 1 shared Annamaria PedotoiD· 1 shared Catherine BirckiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

Víctoriano MuleroORCID

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3 papers

Recent·Most cited

ImmunologyFEBS JournalPeer-reviewedNov 28, 2025

Teleost-specific ictacalcins exhibit similar structural organization, cation-dependent activation and transcriptional regulation as human S100 proteins

Liz Hernández, Théo Paris, Maria Demou…·Laure Yatime

The paper characterizes two teleost-specific S100 proteins, S100i1 and S100i2, showing they share structural, functional, and expression features with mammalian S100 proteins.

1 citation

zebrafishproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintFeb 20, 2025

Inhibition of NLRP1 Inflammasome Activation by Tyrosine Kinase Inhibitors Restores Erythropoiesis in Diamond-Blackfan Anemia Syndrome

Juan M. Lozano Gil, Lola Rodríguez‐Ruiz, Manuel Palacios…·Víctoriano Mulero

This study shows that tyrosine kinase inhibitors can restore erythropoiesis in Diamond-Blackfan Anemia by inhibiting NLRP1 inflammasome activation.

1 citation

humanzebrafish

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 22, 2025

Macrophage Inflammasome Activation Drives Anti-inflammatory Responses via Neutrophil-Derived ASC Speck Transfer and Gasdermin-Dependent Caspase-1 Inhibition

Annamaria Pedoto, Juan M. Lozano Gil, Mai Nguyen Chi…·Víctoriano Mulero

This study shows macrophage inflammasomes drive anti-inflammatory responses by transferring neutrophil-derived ASC specks and inhibiting caspase-1 via Gasdermin E.

1 citation

zebrafishexperimental assay

𝕏 PostBluesky