Systems BiologybioRxivPreprint
Unravelling drug resistant proteotypes through phenotype-resolved proteomics of single-cell derived colonies
Di Qin, Ridhima Das, Simon Schallenberg…·Fabian Coscia
This paper introduces PhenoSCoP, a framework that uses single-cell proteomics and microscopy to identify drug-resistant proteotypes in cancer cells and their progression in patient tissues.
DOI 10.1101/2025.10.11.681009